EFFECT OF ADEMETHIONINE ON THE PROTEOLITIC AND FIBRINOLYTIC ACTIVITY IN KIDNEYS OF RATS WITH RABDOMYOLITIC ACUTE KIDNEY INJURY
V Drachuk, I Zamorskii, T Shchudrova… - Modern engineering …, 2023 - moderntechno.de
V Drachuk, I Zamorskii, T Shchudrova, T Kopchuk, О Goroshko, M Dikal
Modern engineering and innovative technologies, 2023•moderntechno.de… In terms of the proteolytic activity of the kidney tissue, inhibition of the lysis of collagen,
low- and high-molecular proteins was found. The use of ademethionine led to the
restoration of proteolytic and fibrinolytic activity in the kidneys under the conditions of the
development of rhabdomyolytic acute kidney injury. … The obtained results indicate the
ability of ademetionine to restore proteolytic and fibrinolytic activity in the kidneys under the
conditions of the development of rhabdomyolytic acute renal failure, which reduces the risk …
low- and high-molecular proteins was found. The use of ademethionine led to the
restoration of proteolytic and fibrinolytic activity in the kidneys under the conditions of the
development of rhabdomyolytic acute kidney injury. … The obtained results indicate the
ability of ademetionine to restore proteolytic and fibrinolytic activity in the kidneys under the
conditions of the development of rhabdomyolytic acute renal failure, which reduces the risk …
Abstract
In an experimental study on a model of rhabdomyolysis-induced acute kidney injury, the dynamics of the main indicators of the proteolytic and fibrinolytic system were found. In the animals of the group of model pathology, inhibition of the fibrinolysis s
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