GASTROESOPHAGEAL REFLUX DISEASE : A MODERN VIEW OF CAUSES AND CONSEQUENCES
DOI:
https://doi.org/10.30890/2567-5273.2025-37-02-039Keywords:
gastroesophageal reflux disease, heartburn, reflux, risk factorsAbstract
Gastroesophageal reflux disease is one of the most common diseases of the esophagus, which manifests itself with unpleasant symptoms due to the retrograde flow of gastric contents into the esophagus. Common symptoms include heartburn, burning chest pain,Metrics
References
Yuan S, Larsson SC. Adiposity, diabetes, lifestyle factors and risk of gastroesophageal reflux disease: a Mendelian randomization study. Eur J Epidemiol. 2022 Jul;37(7):747-754. doi: 10.1007/s10654-022-00842-z. Epub 2022 Feb 4. PMID: 35119566; PMCID: PMC9329382.
Kim SY, Jung HK, Lim J, Kim TO, Choe AR, Tae CH, Shim KN, Moon CM, Kim SE, Jung SA. Gender Specific Differences in Prevalence and Risk Factors for Gastro-Esophageal Reflux Disease. J Korean Med Sci. 2019 Jun 2;34(21):e158. doi: 10.3346/jkms.2019.34.e158. PMID: 31144481; PMCID: PMC6543060.
Clarrett DM, Hachem C. Gastroesophageal Reflux Disease (GERD). Mo Med. 2018 May-Jun;115(3):214-218. PMID: 30228725; PMCID: PMC6140167.
Richter JE, Rubenstein JH. Presentation and Epidemiology of Gastroesophageal Reflux Disease. Gastroenterology. 2018 Jan;154(2):267-276. doi: 10.1053/j.gastro.2017.07.045. Epub 2017 Aug 3. PMID: 28780072; PMCID: PMC5797499.
Wang K, Wang S, Chen Y, Lu X, Wang D, Zhang Y, Pan W, Zhou C, Zou D. Causal relationship between gut microbiota and risk of gastroesophageal reflux disease: a genetic correlation and bidirectional Mendelian randomization study. Front Immunol. 2024 Feb 21;15:1327503. doi: 10.3389/fimmu.2024.1327503. PMID: 38449873; PMCID: PMC10914956.
Kia L, Pandolfino JE, Kahrilas PJ. Biomarkers of Reflux Disease. Clin Gastroenterol Hepatol. 2016 Jun;14(6):790-797. doi: 10.1016/j.cgh.2015.09.014. Epub 2015 Sep 25. PMID: 26404867; PMCID: PMC4808459.
Sadafi S, Azizi A, Pasdar Y, Shakiba E, Darbandi M. Risk factors for gastroesophageal reflux disease: a population-based study. BMC Gastroenterol. 2024 Feb 5;24(1):64. doi: 10.1186/s12876-024-03143-9. PMID: 38317085; PMCID: PMC10840240.
Nirwan JS, Hasan SS, Babar ZU, Conway BR, Ghori MU. Global Prevalence and Risk Factors of Gastro-oesophageal Reflux Disease (GORD): Systematic Review with Meta-analysis. Sci Rep. 2020 Apr 2;10(1):5814. doi: 10.1038/s41598-020-62795-1. PMID: 32242117; PMCID: PMC7118109.
Eusebi LH, Ratnakumaran R, Yuan Y, Solaymani-Dodaran M, Bazzoli F, Ford AC. Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis. Gut. 2018 Mar;67(3):430-440. doi: 10.1136/gutjnl-2016-313589. Epub 2017 Feb 23. PMID: 28232473.
Yu C, Wang T, Gao Y, Jiao Y, Jiang H, Bian Y, Wang W, Lin H, Xin L, Wang L. Association between physical activity and risk of gastroesophageal reflux disease: A systematic review and meta-analysis. J Sport Health Sci. 2024 Sep;13(5):687-698. doi: 10.1016/j.jshs.2024.03.007. Epub 2024 Mar 27. PMID: 38552714; PMCID: PMC11282378.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Authors
This work is licensed under a Creative Commons Attribution 4.0 International License.
